diff --git a/pulp_file/app/tasks/synchronizing.py b/pulp_file/app/tasks/synchronizing.py
index e7eaca0a23..55d59e1cc1 100644
--- a/pulp_file/app/tasks/synchronizing.py
+++ b/pulp_file/app/tasks/synchronizing.py
@@ -114,7 +114,7 @@ async def run(self):
 
             for entry in entries:
                 path = os.path.join(root_dir, entry.relative_path)
-                url = urlunparse(parsed_url._replace(path=path))
+                url = urlunparse(parsed_url._replace(path=quote(path, safe=":/")))
                 file = FileContent(relative_path=entry.relative_path, digest=entry.digest)
                 artifact = Artifact(size=entry.size, sha256=entry.digest)
                 da = DeclarativeArtifact(