In this repository (folder:Result) you can find the whole-brain thalamic co-activation maps that were created in our meta-analysis: "Flexible and specific contributions of thalamic subdivisions to human cognition" (Antonucci et al., Neuroscience and Biobehavioral Reviews, 2021 https://doi.org/10.1016/j.neubiorev.2021.01.014). In our study, we performed a literature search on Pubmed to extract studies that investigated functional MRI activity across several task domains and that reported results on the thalamus. More specifically, our hierarchical inclusion criteria were:
1 article is in English
2 article is not an animal study
3 article reports original data == is not a review
4 article reports a group of subjects == is not a single case study
5 article reports results of neuroimaging on task-based fMRI
6 article reports data of healthy group and is not reported only as comparison with disease
7 healthy control group is in a baseline/normal condition (e.g. without medication)
8 article reports coordinate-based results
9 article reports whole brain analyses (i.e., no region of interest study)
10 article reports coordinates meeting significance requirements (at least p < 0.001 uncorrected)
11 coordinates report significant results located in the thalamus
12 article reports coordinates in standard stereotactic (MNI or Talairach) space
13 task taps one of the predefined cognitive processes of interest
(attention, working memory, long term memory – encoding, long term memory – retrieval, perception, social cognition, semantic memory) and contrast compares higher level with either lower level or baseline condition
14 the study reports activation analysis results and not only connectivity results
15 the study reports a sample size n > 9
Overall, we included 93 studies that were parsed in different cognitive domains by 2 independent researchers separately. Across domains 1945 participants were included (see below Flow-diagram).
To perform our meta-analysis we used the anisotropic effect-size seed-based mapping software (AES-SDM v.5.15 for Windows 64 bits, http://www.sdmproject.com; (Radua and Mataix-Cols, 2009; Radua et al., 2014). Details on this method can be found for example in Radua and Mataix-Cols, 2012.
See whole-brain thalamic co-activation map across different cognitive domains
In case of any questions feel free to contact me ([email protected]).
References
Antonucci, L. A., Penzel, N., Pigoni, A., Dominke, C., Kambeitz, J., & Pergola, G. (2021). Flexible and specific contributions of thalamic subdivisions to human cognition. Neuroscience & Biobehavioral Reviews.
Radua, J., & Mataix-Cols, D. (2009). Voxel-wise meta-analysis of grey matter changes in obsessive–compulsive disorder. The British Journal of Psychiatry, 195(5), 393-402.
Radua, J., Mataix-Cols, D., Phillips, M. L., El-Hage, W., Kronhaus, D. M., Cardoner, N., & Surguladze, S. (2012). A new meta-analytic method for neuroimaging studies that combines reported peak coordinates and statistical parametric maps. European psychiatry, 27(8), 605-611.
Radua, J., Rubia, K., Canales, E. J., Pomarol-Clotet, E., Fusar-Poli, P., & Mataix-Cols, D. (2014). Anisotropic kernels for coordinate-based meta-analyses of neuroimaging studies. Frontiers in psychiatry, 5, 13.
If you use these whole-brain thalamus co-activation maps in your study, please cite: Antonucci, L. A., Penzel, N., Pigoni, A., Dominke, C., Kambeitz, J., & Pergola, G. (2021). Flexible and specific contributions of thalamic subdivisions to human cognition. Neuroscience & Biobehavioral Reviews.