diff --git a/docs/types.rst b/docs/types.rst
index 2802558..65b8787 100644
--- a/docs/types.rst
+++ b/docs/types.rst
@@ -488,6 +488,14 @@ Outputs as:
    }
 
 
+:class:`typing.Literal`
+~~~~~~~~~~~~~~~~~~~~~~~
+
+Avro schema: schema corresponding to the type of the literal value, e.g. ``string``, ``long`` etc.
+
+Mixed types, e.g. ``Literal["", 42]`` are not supported.
+
+
 :class:`uuid.UUID`
 ~~~~~~~~~~~~~~~~~~
 
diff --git a/src/py_avro_schema/_schemas.py b/src/py_avro_schema/_schemas.py
index db2692b..6701e87 100644
--- a/src/py_avro_schema/_schemas.py
+++ b/src/py_avro_schema/_schemas.py
@@ -36,7 +36,6 @@
     List,
     Literal,
     Optional,
-    Set,
     Tuple,
     Type,
     Union,
@@ -312,11 +311,11 @@ def data(self, names: NamesType) -> JSONObj:
 
 
 class LiteralSchema(Schema):
-    """An Avro schema of any type for a Python Literal type, e.g. Literal[""]"""
+    """An Avro schema of any type for a Python Literal type, e.g. ``Literal[""]``"""
 
     def __init__(self, py_type: Type[Any], namespace: Optional[str] = None, options: Option = Option(0)):
         """
-        An Avro schema of any type for a Python Literal type, e.g. Literal[""]
+        An Avro schema of any type for a Python Literal type, e.g. ``Literal[""]``
 
         :param py_type:   The Python class to generate a schema for.
         :param namespace: The Avro namespace to add to schemas.
@@ -324,27 +323,25 @@ def __init__(self, py_type: Type[Any], namespace: Optional[str] = None, options:
         """
         super().__init__(py_type, namespace=namespace, options=options)
         py_type = _type_from_annotated(py_type)
-        literal_type = self._literal_value_types(py_type).pop()
+        # For now we support Literals with the same type only. Potentially we could explose multiple literal types into
+        # an Avro Union schema, but that may not be something that anyone would every want to use...
+        try:
+            (literal_type,) = {type(literal_value) for literal_value in get_args(py_type)}
+        except ValueError:  # Too many values to unpack
+            raise TypeError("Cannot generate Avro schema for Python typing.Literal with mixed type values")
+
         self.literal_value_schema = _schema_obj(literal_type, namespace=namespace, options=options)
 
     @classmethod
     def handles_type(cls, py_type: Type[Any]) -> bool:
         """Whether this schema class can represent a given Python class"""
         py_type = _type_from_annotated(py_type)
-        literal_value_types = cls._literal_value_types(py_type)
-        # For now we support Literals with the same type only. Potentially we could explose multiple literal types into
-        # an Avro Union schema, but that may not be something that anyone would every want to use...
-        return get_origin(py_type) is Literal and len(literal_value_types) == 1
+        return get_origin(py_type) is Literal
 
     def data(self, names: NamesType) -> JSONType:
         """Return the schema data"""
         return self.literal_value_schema.data(names=names)
 
-    @staticmethod
-    def _literal_value_types(py_type) -> Set[Type[Any]]:
-        """Return the Python types corresponding to the literal values"""
-        return {type(literal_value) for literal_value in get_args(py_type)}
-
 
 class DictAsJSONSchema(Schema):
     """An Avro string schema representing a Python Dict[str, Any] or List[Dict[str, Any]] assuming JSON serialization"""
diff --git a/tests/test_primitives.py b/tests/test_primitives.py
index ebd56aa..7653414 100644
--- a/tests/test_primitives.py
+++ b/tests/test_primitives.py
@@ -354,9 +354,11 @@ def test_union_of_union_string_int():
 
 def test_literal_different_types():
     py_type = Literal["", 42]
-    expected = {}
-    with pytest.raises(pas.TypeNotSupportedError):
-        assert_schema(py_type, expected)
+    with pytest.raises(
+        TypeError,
+        match=re.escape("Cannot generate Avro schema for Python typing.Literal with mixed type values"),
+    ):
+        py_avro_schema._schemas.schema(py_type)
 
 
 def test_optional_str():