A federated web application to search for eQTL/epigenetic signal-associated variants and merge bigWig tracks by genotype.
A production instance with data from Aracena et al. (2024) is available at https://computationalgenomics.ca/tools/epivar.
The tool itself is described in a 2023 preprint:
EpiVar Browser: advanced exploration of epigenomics data under controlled access
David R Lougheed, Hanshi Liu, Katherine A Aracena, Romain Grégoire, Alain Pacis, Tomi Pastinen, Luis B Barreiro, Yann Joly, David Bujold, Guillaume Bourque
bioRxiv 2023.08.03.551309; doi: https://doi.org/10.1101/2023.08.03.551309
- Setting up an EpiVar node
- Working with the EpiVar Browser production instance (for C3G employees)
- Developing EpiVar
- Old setup guide (deprecated)
The EpiVar Browser's server component can be deployed with other data than just the Aracena et al. dataset. The instructions below must be followed, paying especially close attention to the formats described the node setup guide.