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Merge pull request #20 from vivekbhr/master
updates for conda
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## v0.3.4 (25 May 2018) | ||
- made the installation changes for conda | ||
- fixed --dir name in tag2sort | ||
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## v0.3.3_dev (04 Sept 2017)] | ||
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- Fixed output-path handling for paired-end and Hi-C mode (was only working for single-end files). | ||
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@@ -13,8 +17,8 @@ | |
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- In certain cases, specific SNPs were only used for the allele assignment if they were methylated. In more detail: In cases where the SNP was either C/G (REF/ALT) or G/C (REF/ALT), and the read was on the opposing strand, only the methylated form of the C on the reverse strand had previously been allowed as a valid expected base. This has now been changed so that both G and A are considered valid for the strain containing a G at the SNP position (see also this [issue](https://github.com/FelixKrueger/SNPsplit/issues/11)). | ||
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- Changed the way in which C>T SNPs are handled in the allele-tagging report (note that this was merely a report/interpretation thing and did not have any effect the on the actual results). Previously, reads without a call for genome 1 or genome 2 had been listed as: | ||
_reads did not contain one of the expected bases at known SNP positions_. | ||
- Changed the way in which C>T SNPs are handled in the allele-tagging report (note that this was merely a report/interpretation thing and did not have any effect the on the actual results). Previously, reads without a call for genome 1 or genome 2 had been listed as: | ||
_reads did not contain one of the expected bases at known SNP positions_. | ||
In a bisulfite setting this also included C>T SNPs however, and hence the number could have been rather high (>10%). I have now changed this so that reads which had at least one C>T SNP and were unassignable at the same time are scored differently: | ||
_reads that were unassignable contained C>T SNPs preventing the assignment_ | ||
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@@ -26,7 +30,7 @@ _reads that were unassignable contained C>T SNPs preventing the assignment_ | |
#### SNPsplit | ||
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- Changed the `samtools` command throughout SNPsplit to now correctly use the path supplied by the user with `--samtools_path`. Thanks to Kenzo Hillion for spotting this (see [here](https://github.com/FelixKrueger/SNPsplit/commit/77286e1e1ad686ef5e6efcdbda826fcd5e4a5ce2)). | ||
- Changed the `samtools` command throughout SNPsplit to now correctly use the path supplied by the user with `--samtools_path`. Thanks to Kenzo Hillion for spotting this (see [here](https://github.com/FelixKrueger/SNPsplit/commit/77286e1e1ad686ef5e6efcdbda826fcd5e4a5ce2)). | ||
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- Option `--genome_build [NAME]` should now work as intended (used to be `--build` only). | ||
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@@ -59,7 +63,7 @@ _reads that were unassignable contained C>T SNPs preventing the assignment_ | |
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- Option `--genome_build [NAME]` should now work as intended (used to be `--build` only). | ||
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- Added a new version of the genome preparation script that can deal with the latest version of the VCF file for the old NCBIM37 genome build (`mgp.v2.snps.annot.reformat.vcf.gz`). The script is called `SNPsplit_genome_preparation_v2VCF` and may be found in the folder `outdated_VCF_versions` on Github. | ||
- Added a new version of the genome preparation script that can deal with the latest version of the VCF file for the old NCBIM37 genome build (`mgp.v2.snps.annot.reformat.vcf.gz`). The script is called `SNPsplit_genome_preparation_v2VCF` and may be found in the folder `outdated_VCF_versions` on Github. | ||
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## v0.3.1 (18 Jul 2016) | ||
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@@ -125,4 +129,3 @@ SNPsplit_genome_preparation may be run in two different modes: | |
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Feedback or bugs can be sent to: [email protected] | ||
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